Yes! Flair is an official Honeywell integration partner.
Flair Pucks and Smart Vents work with Honeywell Home Wi-Fi thermostats, including X-Series, ElitePRO, T-Series, Lyric, and VisionPRO models.
Flair also supports Honeywell Home Smart Room Sensors used with T9, T10, and X-Series thermostats.
The Honeywell Home thermostats and Smart Room Sensors above can be used as the temperature-sensing device in a Flair room to automate Smart Vent operation.